Description

(R)-Methyl 5-(6-(Pivaloyloxymethyl)-1H-Benzo[D]Imidazol-1-Yl)-3-(1-(2-(Trifluoromethyl)Phenyl)Ethoxy)Thiophene-2-Carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure incorporating benzimidazole and thiophene moieties. This compound is critical for the synthesis of targeted therapeutic agents, particularly in the development of novel enzyme inhibitors and receptor modulators. It is primarily required by research institutions and pharmaceutical companies engaged in the discovery and process development of new chemical entities.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of proprietary drug candidates, especially those targeting specific enzymatic pathways.
• Biochemical Research: Used as a reference standard or a probe molecule in pharmacological and mechanism-of-action studies.
• Process Chemistry: Serves as a critical intermediate in the scale-up and optimization of active pharmaceutical ingredient (API) manufacturing routes.
• Preclinical Development: Employed in the production of compounds for toxicology, pharmacokinetics, and formulation studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	(R)-Methyl 5-(6-(Pivaloyloxymethyl)-1H-Benzo[D]Imidazol-1-Yl)-3-(1-(2-(Trifluoromethyl)Phenyl)Ethoxy)Thiophene-2-Carboxylate
CAS No.	929095-38-5
Molecular Formula	C30H28F3N3O5S
Molecular Weight	599.62 g/mol
Synonyms	Methyl (R)-5-[6-[(2,2-dimethylpropanoyloxy)methyl]-1H-benzimidazol-1-yl]-3-[1-[2-(trifluoromethyl)phenyl]ethoxy]thiophene-2-carboxylate; 929095-38-5; (R)-Methyl 5-(6-(Pivaloyloxymethyl)-1H-Benzo[D]Imidazol-1-Yl)-3-(1-(2-(Trifluoromethyl)Phenyl)Ethoxy)Thiophene-2-Carboxylate; UNII-8F1Q8V31Q8; 8F1Q8V31Q8; SCHEMBL23306277; DTXSID701125938; BCP31033
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems, ensuring batch-to-batch consistency and high purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles. We support development needs with custom purity grades and specifications aligned with cGMP principles for pharmaceutical research.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light) and should be handled with appropriate precautions for materials soluble in strong acids/organic solvents. Keep the container tightly sealed in a dry environment to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.