Description

2,3-Dihydro-Indole-1,6-Dicarboxylic Acid 1-tert-Butyl Ester 6-Methyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its specific ester-protected indoline scaffold. This compound matters as a critical building block in the synthesis of complex molecules, offering chemists precise control over reactivity and functional group manipulation. It is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides due to its heterocyclic structure.
• Organic Synthesis Building Block: Serves as a versatile precursor for constructing complex indoline-based molecular architectures in academic and industrial research.
• Material Science Research: Potential application in the development of organic semiconductors and specialty polymers.
• Contract Manufacturing (CMO): Supplied to custom synthesis organizations for scale-up and production under cGMP conditions.

Basic Information

Product Name	2,3-Dihydro-Indole-1,6-Dicarboxylic Acid 1-tert-Butyl Ester 6-Methyl Ester
CAS No.	928771-49-7
Molecular Formula	C16H21NO4
Molecular Weight	291.34 g/mol
Synonyms	1-(tert-Butyl) 6-methyl 2,3-dihydro-1H-indole-1,6-dicarboxylate; 1H-Indole-1,6-dicarboxylic acid, 2,3-dihydro-, 1-(1,1-dimethylethyl) 6-methyl ester; 2,3-Dihydroindole-1,6-dicarboxylic Acid 1-tert-Butyl Ester 6-Methyl Ester; tert-Butyl methyl 2,3-dihydro-1H-indole-1,6-dicarboxylate; Methyl 1-(tert-butoxycarbonyl)-2,3-dihydro-1H-indole-6-carboxylate
EINECS	Contact for details

Quality Control

Our 2,3-Dihydro-Indole-1,6-Dicarboxylic Acid 1-tert-Butyl Ester 6-Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.