Description

6-(Bromotriphenylphosphoranyl)Hexanoic Acid is a specialized organophosphorus compound widely used as a key reagent in organic synthesis. This compound matters for its role as a versatile Wittig-Horner reagent, enabling the efficient formation of carbon-carbon double bonds to create complex organic molecules. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing specific molecular architectures.

Application

• Pharmaceutical Intermediate Synthesis: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly those containing alkene functionalities.
• Agrochemical Production: Used in the development and manufacturing of novel pesticides and herbicides requiring specific olefination steps.
• Material Science Research: Employed in the creation of functionalized polymers, liquid crystals, and other advanced organic materials via olefination reactions.
• Academic & Industrial R&D: Serves as a fundamental reagent in method development and exploratory synthesis for new chemical entities.
• Peptide & Bioconjugate Chemistry: Facilitates the introduction of lipophilic chains or fluorescent probes onto biomolecules through its carboxylic acid handle.
• Catalyst Ligand Precursor: Can be utilized as a precursor for phosphine-based ligands used in transition metal catalysis.

Basic Information

Product Name	6-(Bromotriphenylphosphoranyl)Hexanoic Acid
CAS No.	928753-93-9
Molecular Formula	C30H28BrO2P
Molecular Weight	531.42 g/mol
Synonyms	6-(Bromotriphenylphosphoranyl)hexanoic acid; 6-(Triphenylphosphonio)hexanoic acid bromide; 6-(Bromotriphenylphosphoniumyl)hexanoic acid; 6-Carboxyhexyltriphenylphosphonium bromide; (6-Carboxyhexyl)triphenylphosphonium bromide; Hexanoic acid, 6-(bromotriphenylphosphoranyl)-; TPHP-Hex-COOH-Br; Wittig-Horner reagent C6-acid bromide
EINECS	Contact for details

Quality Control

Our 6-(Bromotriphenylphosphoranyl)Hexanoic Acid is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with research-grade specifications. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.