Description

4-Fluoroisoquinolin-5-Amine is a high-value fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where the introduction of fluorine atoms is a critical strategy for modulating biological activity and metabolic stability. It is primarily needed by research and development chemists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides, leveraging the fluorine atom for enhanced efficacy and environmental profile.
• Material Science Precursor: Serves as a monomer or functionalizing agent in the creation of advanced polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probe: Employed in medicinal chemistry for structure-activity relationship (SAR) studies and as a fluorescent tag or labeling reagent due to its aromatic amine functionality.
• Academic & Contract Research: Essential for synthetic methodology development and exploratory research in academic institutions and contract research organizations (CROs).

Basic Information

Product Name	4-Fluoroisoquinolin-5-Amine
CAS No.	928664-14-6
Molecular Formula	C9H7FN2
Molecular Weight	162.16 g/mol
Synonyms	5-Amino-4-fluoroisoquinoline; 4-Fluoro-5-aminoisoquinoline; 4-Fluoro-isoquinolin-5-ylamine; 4-Fluoro-5-isoquinolinamine; 928664-14-6; 4-Fluoroisoquinoline-5-amine; 5-Isoquinolinamine, 4-fluoro-
EINECS	Contact for details

Quality Control

Our 4-Fluoroisoquinolin-5-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistent performance. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your R&D and scale-up activities with reliable data and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.