Description

(R,S)-1-Tosyl Glycerol-D5 is a deuterium-labeled derivative of 1-tosyl glycerol, a key synthetic intermediate and analytical standard. This compound is specifically valued for its use in quantitative mass spectrometry and metabolic pathway tracing studies, where the stable isotope label provides a distinct mass signature. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and life science sectors who require high-purity, isotopically labeled building blocks for drug development and biochemical research.

Application

• Internal Standard for LC-MS/MS Analysis: Used as a quantitative reference standard in bioanalytical method development and validation for pharmacokinetic studies.
• Metabolic Pathway Tracing: Employed in deuterium labeling experiments to investigate the metabolism and biotransformation of glycerol-based compounds in biological systems.
• Synthetic Intermediate: Serves as a protected, labeled precursor in the multi-step synthesis of complex molecules, including deuterated lipids, pharmaceuticals, and specialty chemicals.
• Proteomics & Lipidomics Research: A critical tool in mass spectrometry-based 'omics studies for the accurate identification and quantification of related metabolites.
• Quality Control & Method Development: Utilized in analytical laboratories to develop and calibrate methods for the detection of non-labeled 1-tosyl glycerol or related impurities.

Basic Information

Product Name	(R,S)-1-Tosyl Glycerol-D5
CAS No.	928623-32-9
Molecular Formula	C10H7D5O5S
Molecular Weight	247.31 g/mol
Synonyms	1-O-Tosylglycerol-d5; (Rac)-1-Tosylglycerol-d5; 1-Tosyl-sn-glycerol-d5; Glycerol 1-(p-toluenesulfonate)-d5; 2,3-Dihydroxypropyl 4-methylbenzenesulfonate-d5; Deuterated 1-Tosyl glycerol; 1-O-(p-Tolylsulfonyl)glycerol-d5; Toluene-4-sulfonic acid 2,3-dihydroxy-propyl ester-d5
EINECS	Contact for details

Quality Control

Our (R,S)-1-Tosyl Glycerol-D5 is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and MS, to confirm isotopic purity (D-enrichment), chemical purity, and identity. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C in a cool, dry place. The compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-enrichment)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.