Description

1-(Thien-2-Ylcarbonyl)Indolin-6-Amine is a high-purity, advanced pharmaceutical intermediate featuring a unique indole-thiophene hybrid scaffold. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates targeting a range of therapeutic areas. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new chemical entities, particularly for central nervous system (CNS) and oncology applications.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel small-molecule drug candidates, particularly those targeting neurological receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its privileged heterocyclic structure.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study biological pathways and protein functions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects.
• Library Synthesis: A valuable building block for creating diverse compound libraries for high-throughput screening (HTS).
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and drug discovery methodologies.

Basic Information

Product Name	1-(Thien-2-Ylcarbonyl)Indolin-6-Amine
CAS No.	927997-00-0
Molecular Formula	C13H12N2OS
Molecular Weight	244.31 g/mol
Synonyms	1-(Thiophene-2-carbonyl)indolin-6-amine; 6-Amino-1-(2-thienylcarbonyl)indoline; 1-(2-Thienylcarbonyl)-6-indolinamine; 1-(Thiophen-2-ylcarbonyl)-2,3-dihydro-1H-indol-6-amine; 6-Amino-1-(thiophene-2-carbonyl)indoline; 1-(Thien-2-Ylcarbonyl)Indolin-6-Amine; 1-(2-Thienoyl)-6-aminoindoline; 927997-00-0
EINECS	Contact for details

Quality Control

Our 1-(Thien-2-Ylcarbonyl)Indolin-6-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and analytical results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.