Description

1-(Cyclopropylcarbonyl)Indolin-5-Amine is a high-purity, advanced pharmaceutical intermediate featuring a unique indoline scaffold modified with a cyclopropylcarbonyl group. This compound is valued for its role as a critical building block in the synthesis of novel bioactive molecules, particularly in medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new therapeutic agents, especially within the fields of oncology and central nervous system (CNS) disorders.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates targeting specific biological pathways.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• API Development: Serves as a building block in the multi-step synthesis of potential Active Pharmaceutical Ingredients (APIs).
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and receptor interactions.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthetic routes.
• Academic Research: Used in university and institutional labs for exploratory synthetic chemistry and pharmacological studies.

Basic Information

Product Name	1-(Cyclopropylcarbonyl)Indolin-5-Amine
CAS No.	927996-72-3
Molecular Formula	C12H14N2O
Molecular Weight	202.25 g/mol
Synonyms	5-Amino-1-(cyclopropylcarbonyl)indoline; 1-(Cyclopropanecarbonyl)-2,3-dihydro-1H-indol-5-amine; 5-Aminoindoline-1-cyclopropylmethanone; 1H-Indol-5-amine, 2,3-dihydro-1-(1-oxocyclopropyl)-; Indolin-5-amine, 1-(cyclopropylcarbonyl)-
EINECS	Contact for details

Quality Control

Our 1-(Cyclopropylcarbonyl)Indolin-5-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.