Description

1-Chloro-4-Iodoisoquinoline is a versatile halogenated isoquinoline derivative, a key building block in advanced organic synthesis. Its value lies in its dual halogen functionality, which provides distinct reactive sites for selective cross-coupling and functionalization reactions. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing novel active ingredients and complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, especially in kinase inhibitor research and other therapeutic small molecules.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a building block for creating organic electronic materials, ligands for catalysts, and specialty polymers.
• Cross-Coupling Reactions: The iodine and chlorine atoms make it an excellent substrate for Suzuki, Stille, and Sonogashira coupling reactions to form complex biaryl systems.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological processes and target identification.
• Academic & R&D Laboratories: A valuable reagent for methodological development in organic chemistry and exploring new synthetic pathways.

Basic Information

Product Name	1-Chloro-4-Iodoisoquinoline
CAS No.	927801-77-2
Molecular Formula	C9H5ClIN
Molecular Weight	289.50 g/mol
Synonyms	4-Iodo-1-chloroisoquinoline; 1-Chloro-4-iodo-isoquinoline; Isoquinoline, 1-chloro-4-iodo-; 1-Chloro-4-iodoisoquinoline; 927801-77-2; 4-Iodo-1-chloro-isoquinoline; 1-Chloro-4-iodo-2-azanaphthalene
EINECS	Contact for details

Quality Control

Our 1-Chloro-4-Iodoisoquinoline is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting purity, assay, and impurity profiles to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials. The container should be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.