Description

8-Bromo-5-Chloroisoquinoline is a high-purity halogenated isoquinoline derivative, a crucial advanced intermediate in modern organic synthesis. Its value lies in providing a versatile, multi-functional scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, especially kinase inhibitors and other biologically active heterocycles.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides due to its bioactive heterocyclic core.
• Material Science Precursor: Serves as a starting material for creating organic ligands in catalysis and functional organic materials.
• Chemical Biology Probe Development: Utilized in the design and synthesis of molecular probes for studying biological pathways and target engagement.
• Academic & Contract Research: Essential for methodological development and novel synthetic route exploration in university and CRO laboratories.
• Custom Synthesis: Acts as a foundational substrate for the tailored production of specialty chemicals and fine chemicals.

Basic Information

Product Name	8-Bromo-5-Chloroisoquinoline
CAS No.	927801-25-0
Molecular Formula	C9H5BrClN
Molecular Weight	242.50 g/mol
Synonyms	8-Bromo-5-chloro-isoquinoline; 5-Chloro-8-bromoisoquinoline; Isoquinoline, 8-bromo-5-chloro-; 8-Bromo-5-chloroisoquinoline; 927801-25-0; SCHEMBL2188307; AKOS040759232; ZINC000257046531
EINECS	Contact for details

Quality Control

Our 8-Bromo-5-Chloroisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and GC-MS to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with every shipment, documenting all critical quality attributes. Our standard grade meets the stringent requirements for research and development use, with purity typically ≥95% (HPLC). Custom synthesis to higher purity grades (≥98% or ≥99%) is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.