Description

4-Bromo-1-Iodoisoquinoline is a high-value halogenated isoquinoline derivative, serving as a critical building block in advanced organic synthesis. Its unique bifunctional halogenated structure makes it an indispensable reagent for constructing complex heterocyclic frameworks and pharmaceutical intermediates. This compound is primarily utilized by research institutions and chemical manufacturers specializing in medicinal chemistry, agrochemical development, and materials science.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting kinase inhibition and other therapeutic areas.
• Agrochemical Synthesis: Used in the development of new pesticides and herbicides, leveraging the isoquinoline core for biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the creation of organic electronic materials and metal-organic frameworks (MOFs).
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed reactions like Suzuki, Sonogashira, and Buchwald-Hartwig amination due to the reactive bromo and iodo groups.
• Ligand Synthesis: Used to prepare specialized ligands for catalysis and coordination chemistry.
• Chemical Biology: Employed as a probe or tag in bioconjugation and target identification studies.

Basic Information

Product Name	4-Bromo-1-Iodoisoquinoline
CAS No.	927800-97-3
Molecular Formula	C9H5BrIN
Molecular Weight	333.95 g/mol
Synonyms	1-Iodo-4-bromoisoquinoline; Isoquinoline, 4-bromo-1-iodo-; 4-Bromo-1-iodo-isoquinoline; 4-Bromo-1-iodoisoquinoline; 927800-97-3; 4-Br-1-I-isoquinoline
EINECS	Contact for details

Quality Control

Our 4-Bromo-1-Iodoisoquinoline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Melting Point	Contact for details
Heavy Metals	<20 ppm
Residue on Ignition	<0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.