Description

1-Isopropyl-2,3-Dihydro-1H-Indol-6-Ylamine is a versatile indoline derivative featuring an amine functional group, making it a valuable intermediate in advanced organic synthesis. Its core value lies in its role as a key building block for constructing complex heterocyclic frameworks, particularly in the development of active pharmaceutical ingredients (APIs) and specialty agrochemicals. This compound is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries seeking to develop novel bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, due to its indoline scaffold.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, where its structural motif can contribute to biological activity.
• Organic Light-Emitting Diode (OLED) Materials: Acts as a starting material for synthesizing electron-transporting or host materials in OLED device fabrication.
• Ligand and Catalyst Development: The amine group allows for functionalization into chelating ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Dye and Pigment Intermediate: Utilized in the production of specialized indoline-based dyes and functional colorants.
• Academic and Contract Research: A valuable reagent for methodological studies in organic chemistry and for building compound libraries in high-throughput screening.

Basic Information

Product Name	1-Isopropyl-2,3-Dihydro-1H-Indol-6-Ylamine
CAS No.	927684-86-4
Molecular Formula	C11H16N2
Molecular Weight	176.26 g/mol
Synonyms	6-Amino-1-isopropyl-2,3-dihydro-1H-indole; 1H-Indol-6-amine, 2,3-dihydro-1-(1-methylethyl)-; 1-Isopropyl-1,2,3,4-tetrahydro-6-quinolinamine; 1-Isopropyl-6-aminoindoline; 6-Amino-1-isopropylindoline; 1-(Propan-2-yl)-2,3-dihydro-1H-indol-6-amine
EINECS	Contact for details

Quality Control

Our 1-Isopropyl-2,3-Dihydro-1H-Indol-6-Ylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.