Description

3-Formyl-1H-Indole-6-Carboxylic Acid Ethyl Ester is a high-value indole derivative that serves as a versatile and critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a formyl and an ester group on the indole scaffold, makes it an indispensable precursor for constructing complex heterocyclic systems. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon for the development of indole-based drug candidates, including kinase inhibitors, serotonin receptor modulators, and anti-cancer agents.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and plant growth regulators that leverage the indole core structure.
• Material Science Research: Serves as a precursor for functional organic materials, such as organic light-emitting diodes (OLEDs) and conductive polymers.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and the synthesis of complex natural product analogs.
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty dyes, pigments, and fluorescent markers.

Basic Information

Product Name	3-Formyl-1H-Indole-6-Carboxylic Acid Ethyl Ester
CAS No.	927181-97-3
Molecular Formula	C₁₂H₁₁NO₃
Molecular Weight	217.22 g/mol
Synonyms	6-(Ethoxycarbonyl)-1H-indole-3-carboxaldehyde; Ethyl 3-Formyl-1H-indole-6-carboxylate; 1H-Indole-6-carboxylic acid, 3-formyl-, ethyl ester; 3-Formylindole-6-carboxylic Acid Ethyl Ester; 6-Carbethoxyindole-3-carboxaldehyde; Ethyl 6-Carboxyindole-3-carboxylate (deprotected form reference); 3-Carboxaldehyde-1H-indole-6-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Every batch of 3-Formyl-1H-Indole-6-Carboxylic Acid Ethyl Ester is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) specifying purity (typically by HPLC), identity confirmation, and impurity profile is available for each lot upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle under an inert atmosphere for long-term storage or after opening. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.