Description

1-Boc-4-Bromo-1H-Indazole is a high-purity, protected heterocyclic building block of significant importance in modern organic synthesis. This compound serves as a versatile and critical intermediate for the development of novel pharmaceutical agents and advanced materials. It is primarily utilized by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators.
• Material Science: Serves as a building block for organic electronic materials, such as OLEDs and conductive polymers.
• Chemical Biology: Employed in the creation of molecular probes and labeled compounds for biochemical assays and diagnostic tools.
• Custom Synthesis: Utilized by contract research and manufacturing organizations (CROs/CMOs) for bespoke synthesis projects and library production.
• Academic Research: A valuable reagent for methodological development and exploring new chemical reactions in university and institutional laboratories.

Basic Information

Product Name	1-Boc-4-Bromo-1H-Indazole
CAS No.	926922-37-4
Molecular Formula	C₁₂H₁₃BrN₂O₂
Molecular Weight	297.15 g/mol
Synonyms	1-(tert-Butoxycarbonyl)-4-bromo-1H-indazole; 4-Bromo-1H-indazole-1-carboxylic acid tert-butyl ester; tert-Butyl 4-bromo-1H-indazole-1-carboxylate; 4-Bromo-1-((tert-butoxy)carbonyl)-1H-indazole; Boc-4-Br-indazole; 1-Boc-4-bromoindazole; 4-Bromo-1-Boc-indazole; 1-Boc-4-bromo-1H-indazole
EINECS	Contact for details

Quality Control

Our 1-Boc-4-Bromo-1H-Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific project requirements. We adhere to cGMP principles for production relevant to pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.