Description

(5S)-5-Cyclohexyl-2-Pyrrolidinone CAS NO 926622-88-0 is a high-purity, chiral lactam building block of significant interest in advanced organic synthesis. Its value lies in its rigid, functionalized structure, which serves as a key intermediate for constructing complex molecules with defined stereochemistry. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A critical chiral precursor in the synthesis of novel drug candidates, especially for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used as a building block for creating enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Asymmetric Catalysis: Employed as a ligand or a core structure for developing new chiral catalysts and auxiliaries.
• Fine Chemical Production: Serves as a versatile intermediate for manufacturing specialty chemicals, flavors, and fragrances requiring specific stereochemistry.
• Academic & R&D: A valuable reagent for methodological research in organic chemistry, particularly in studies involving lactam chemistry and stereoselective transformations.
• Material Science: Potential monomer or additive for synthesizing specialized polymers with unique thermal or mechanical properties.

Basic Information

Product Name	(5S)-5-Cyclohexyl-2-Pyrrolidinone
CAS No.	926622-88-0
Molecular Formula	C10H17NO
Molecular Weight	167.25 g/mol
Synonyms	(S)-5-Cyclohexylpyrrolidin-2-one; (5S)-5-Cyclohexyl-2-oxopyrrolidine; (S)-5-Cyclohexyl-2-pyrrolidinone; L-5-Cyclohexyl-2-pyrrolidinone; (-)-5-Cyclohexyl-2-pyrrolidinone; (S)-(-)-5-Cyclohexyl-2-pyrrolidinone; 2-Pyrrolidinone, 5-cyclohexyl-, (5S)-; 926622-88-0
EINECS	Contact for details

Quality Control

Our (5S)-5-Cyclohexyl-2-Pyrrolidinone is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.