Description

4-Bromo-3-Chloro-1-Benzothiophene-2-Carboxylic Acid is a high-purity, multi-functional heterocyclic building block of significant importance in advanced organic synthesis. Its core value lies in its unique halogenated benzothiophene scaffold, which serves as a critical intermediate for constructing complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Development: Used in the research and production of advanced pesticides and herbicides, leveraging its halogenated structure for bioactivity.
• Material Science Research: Serves as a building block for organic semiconductors, liquid crystals, and other functional organic materials.
• Chemical Synthesis: A versatile reagent for Suzuki-Miyaura and other cross-coupling reactions to create complex, poly-substituted aromatic systems.
• Dye and Pigment Intermediate: Utilized in the development of specialized dyes and pigments due to the benzothiophene core.
• Academic & R&D: A valuable compound for methodological studies in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	4-Bromo-3-Chloro-1-Benzothiophene-2-Carboxylic Acid
CAS No.	926257-36-5
Molecular Formula	C9H4BrClO2S
Molecular Weight	291.55 g/mol
Synonyms	4-Bromo-3-chlorobenzo[b]thiophene-2-carboxylic acid; 2-Carboxy-4-bromo-3-chlorobenzo[b]thiophene; 4-Bromo-3-chloro-1-benzothiophene-2-carboxylic acid; 926257-36-5; Benzo[b]thiophene-2-carboxylic acid, 4-bromo-3-chloro-; 3-Chloro-4-bromobenzo[b]thiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-Bromo-3-Chloro-1-Benzothiophene-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and away from direct light sources to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.