Description

2-Amino-5-(3-Trifluoromethylphenyl)Thiazole is a high-value, multi-functional heterocyclic building block featuring a thiazole core substituted with an amino group and a trifluoromethylphenyl moiety. This compound is prized for its unique electronic and steric properties, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought after by research institutions and industrial R&D departments engaged in the development of novel pharmaceuticals, agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Serves as a core scaffold for developing new generation herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole ring and the metabolic stability imparted by the trifluoromethyl group.
• Material Science: Used in the research and development of organic electronic materials, such as OLED (Organic Light-Emitting Diode) emitters and charge-transport materials, due to its favorable electron-transport characteristics.
• Ligand Synthesis: Employed in organometallic chemistry to create novel ligands for catalysis, where the nitrogen donors can coordinate to various metal centers to modulate catalytic activity.
• Chemical Biology Probe: Acts as a versatile building block for constructing molecular probes and tags used in biochemical assays and diagnostic research.

Basic Information

Product Name	2-Amino-5-(3-Trifluoromethylphenyl)Thiazole
CAS No.	926224-03-5
Molecular Formula	C10H7F3N2S
Molecular Weight	244.24 g/mol
Synonyms	2-Amino-5-(3-(trifluoromethyl)phenyl)thiazole; 5-(3-Trifluoromethylphenyl)-2-aminothiazole; 2-Thiazolamine, 5-[3-(trifluoromethyl)phenyl]-; 2-Amino-5-(α,α,α-trifluoro-m-tolyl)thiazole; 5-(3-Trifluoromethylphenyl)thiazol-2-amine; 2-Amino-5-(m-trifluoromethylphenyl)thiazole; 2-Amino-5-(3-trifluoromethylphenyl)-1,3-thiazole
EINECS	Contact for details

Quality Control

Our 2-Amino-5-(3-Trifluoromethylphenyl)Thiazole is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment to ensure traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.