Description

5-tert-Butoxycarbonylthiophene-2-Boronic Acid is a high-purity, protected heterocyclic boronic acid derivative essential for modern synthetic chemistry. This compound serves as a critical building block in cross-coupling reactions, enabling the precise construction of complex molecular architectures. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key reagent in Suzuki-Miyaura cross-coupling reactions for synthesizing novel drug candidates, particularly those containing functionalized thiophene cores.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides that require specific thiophene-based structures.
• Material Science: Serves as a monomer or precursor in the creation of conjugated polymers and organic electronic materials for OLEDs and semiconductors.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes, enzyme inhibitors, and bioconjugation reagents.
• Academic & Contract Research: A valuable tool for methodology development and exploring new synthetic pathways in university and CRO laboratories.

Basic Information

Product Name	5-tert-Butoxycarbonylthiophene-2-Boronic Acid
CAS No.	925921-29-5
Molecular Formula	C9H13BO4S
Molecular Weight	228.07 g/mol
Synonyms	2-(Boc-amino)thiophene-5-boronic acid; 5-[(tert-Butoxycarbonyl)amino]thiophene-2-boronic acid; 5-(Boc-amino)thiophene-2-boronic acid; 2-Borono-5-[(tert-butoxycarbonyl)amino]thiophene; 5-tert-Butoxycarbonylaminothiophene-2-boronic acid; N-Boc-5-aminothiophene-2-boronic acid; Boc-Thiophene-2-Boronic Acid
EINECS	Contact for details

Quality Control

Every batch of 5-tert-Butoxycarbonylthiophene-2-Boronic Acid is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including NMR, HPLC, and elemental analysis, to ensure compliance with exacting purity standards for research and development. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.