Description

1-Bromo-4-Chloroisoquinoline is a high-purity halogenated isoquinoline derivative, a crucial building block in advanced organic synthesis. This compound is valued for its dual reactive sites, enabling selective functionalization to create complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in kinase inhibitor and anticancer agent research.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and pesticides, leveraging the isoquinoline scaffold's bioactivity.
• Material Science Research: Serves as a monomer or functional unit in the creation of organic electronic materials, such as OLEDs and conductive polymers.
• Ligand and Catalyst Development: Employed to construct complex chelating ligands for metal catalysis and coordination chemistry applications.
• Chemical Biology Probes: Utilized as a core structure for developing fluorescent tags or molecular probes to study biological processes.
• Custom Synthesis & Scale-Up: An essential starting material for contract research and manufacturing organizations (CROs/CMOs) for custom synthesis projects.

Basic Information

Product Name	1-Bromo-4-Chloroisoquinoline
CAS No.	925890-48-8
Molecular Formula	C9H5BrClN
Molecular Weight	242.50 g/mol
Synonyms	4-Chloro-1-bromoisoquinoline; 1-Bromo-4-chloro-isoquinoline; Isoquinoline, 1-bromo-4-chloro-; 925890-48-8
EINECS	Contact for details

Quality Control

Our 1-Bromo-4-Chloroisoquinoline is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and supporting regulatory filings for research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC, NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.