Description

1-(3-Cyano-Benzyl)-3-Formyl-1H-Indole-5-Carboxylic Acid Methyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its indole-based molecular framework. This compound matters for its critical role as a versatile building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, including kinase inhibitors and other small-molecule drugs targeting various disease pathways.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the multi-step synthesis of targeted drug candidates, especially those with indole or heterocyclic cores.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with potential biological activity.
• Kinase Inhibitor Development: A crucial building block for constructing molecules designed to modulate kinase enzymes, a prominent target class in oncology and inflammatory diseases.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services for the pharmaceutical industry.
• Academic Research: Utilized in university and institutional labs for exploring novel organic reactions and synthesizing complex molecular architectures for biological evaluation.

Basic Information

Product Name	1-(3-Cyano-Benzyl)-3-Formyl-1H-Indole-5-Carboxylic Acid Methyl Ester
CAS No.	925889-73-2
Molecular Formula	C19H14N2O3
Molecular Weight	318.33 g/mol
Synonyms	Methyl 1-[(3-cyanophenyl)methyl]-3-formyl-1H-indole-5-carboxylate; 1-[(3-Cyanobenzyl)]-3-formyl-1H-indole-5-carboxylic Acid Methyl Ester; 3-Formyl-1-(3-cyanobenzyl)-1H-indole-5-carboxylic Acid Methyl Ester; 1-(3-Cyanobenzyl)-3-formylindole-5-carboxylic Acid Methyl Ester; 925889-73-2; CAS 925889-73-2
EINECS	Contact for details

Quality Control

Our 1-(3-Cyano-Benzyl)-3-Formyl-1H-Indole-5-Carboxylic Acid Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is easily oxidized; for long-term storage, consider keeping under an inert atmosphere (e.g., nitrogen or argon). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.