Description

tert-Butyl 4-((6-(2-Aminophenyl)imidazo[2,1-b]thiazol-3-yl)methyl)piperazine-1-carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is critical for the synthesis of novel therapeutic agents, particularly in oncology and targeted drug discovery. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of investigational new drugs (INDs) and active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Research: Serves as a core scaffold for developing potent and selective kinase inhibitors for cancer therapy.
• Medicinal Chemistry: Used in structure-activity relationship (SAR) studies and lead optimization programs.
• Bioconjugation & Probe Development: The reactive amine group allows for conjugation to create targeted molecular probes.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.

Basic Information

Product Name	tert-Butyl 4-((6-(2-Aminophenyl)imidazo[2,1-b]thiazol-3-yl)methyl)piperazine-1-carboxylate
CAS No.	925437-87-2
Molecular Formula	C22H27N5O2S
Molecular Weight	425.55 g/mol
Synonyms	1-Boc-4-((6-(2-aminophenyl)imidazo[2,1-b]thiazol-3-yl)methyl)piperazine; tert-Butyl 4-[(6-(2-aminophenyl)imidazo[2,1-b][1,3]thiazol-3-yl)methyl]piperazine-1-carboxylate; 925437-87-2; BOC-protected aminophenyl-imidazothiazole piperazine; 4-((6-(2-Aminophenyl)imidazo[2,1-b]thiazol-3-yl)methyl)piperazine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-((6-(2-Aminophenyl)imidazo[2,1-b]thiazol-3-yl)methyl)piperazine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with every shipment, detailing all critical quality attributes to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.