Description

(2-Aminothiophen-3-Yl)(4-(Trifluoromethyl)Phenyl)Methanone is a high-value, heterocyclic aromatic ketone building block featuring both an aminothiophene and a trifluoromethylphenyl moiety. This compound is critical for medicinal chemistry and advanced materials research, offering a versatile scaffold for the synthesis of novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating compounds with enhanced biological activity and specific physicochemical properties.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiophene and trifluoromethyl groups.
• Material Science: Acts as a monomer or functional unit in the design of organic semiconductors, liquid crystals, and polymers with tailored electronic properties.
• Chemical Biology Probe Development: Utilized for creating molecular probes to study enzyme function and protein-ligand interactions due to its modifiable amine group.
• Custom Synthesis & Contract Manufacturing: A vital building block for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the global life sciences sector.

Basic Information

Item	Details
Product Name	(2-Aminothiophen-3-Yl)(4-(Trifluoromethyl)Phenyl)Methanone
CAS No.	925005-48-7
Molecular Formula	C12H8F3NOS
Molecular Weight	271.26 g/mol
Synonyms	2-Amino-3-benzoyl-4-(trifluoromethyl)thiophene; [4-(Trifluoromethyl)phenyl](2-amino-3-thienyl)methanone; 2-Amino-3-[4-(trifluoromethyl)benzoyl]thiophene; (2-Amino-3-thienyl)[4-(trifluoromethyl)phenyl]methanone; 925005-48-7; ATFM; 4-Trifluoromethylphenyl 2-aminothiophene-3-yl ketone
EINECS	Contact for details

Quality Control

Every batch of (2-Aminothiophen-3-Yl)(4-(Trifluoromethyl)Phenyl)Methanone is manufactured under strict quality management systems. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and development. A detailed Certificate of Analysis (COA) is supplied with each shipment, confirming identity, purity, and impurity profiles as determined by advanced spectroscopic and chromatographic methods.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.