Description

Methyl 3-Bromo-1-(Cyanomethyl)-1H-Indole-2-Carboxylate is a high-value, multi-functional indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its unique molecular architecture, featuring both bromo and cyanomethyl substituents, makes it an indispensable building block for constructing complex heterocyclic frameworks. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where precise molecular modification is paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex indole-based drug candidates, particularly for oncology and central nervous system (CNS) targets.
• Agrochemical Research: Used in the development of new-generation herbicides, fungicides, and plant growth regulators that require specific indole core structures.
• Material Science: Serves as a monomer or functional unit in the creation of specialty polymers and organic electronic materials.
• Academic & R&D Synthesis: Employed in methodological chemistry research for cross-coupling reactions, cyclizations, and the study of novel heterocyclic systems.
• Chemical Biology Probe Development: Utilized to create molecular probes for studying biological pathways and protein functions.

Basic Information

Product Name	Methyl 3-Bromo-1-(Cyanomethyl)-1H-Indole-2-Carboxylate
CAS No.	924869-15-8
Molecular Formula	C12H9BrN2O2
Molecular Weight	293.12 g/mol
Synonyms	Methyl 3-bromo-1-(cyanomethyl)indole-2-carboxylate; 1H-Indole-2-carboxylic acid, 3-bromo-1-(cyanomethyl)-, methyl ester; 3-Bromo-1-(cyanomethyl)-1H-indole-2-carboxylic acid methyl ester; 924869-15-8; Methyl 3-bromo-1-cyanomethylindole-2-carboxylate
EINECS	Contact for details

Quality Control

Our production of Methyl 3-Bromo-1-(Cyanomethyl)-1H-Indole-2-Carboxylate adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, identity, and impurity profiles. Our quality management system is designed to support cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.