Description

n-[5-(4-Chlorobenzyl)-1,3-Thiazol-2-Yl]-3,4-Dihydro-2H-Chromene-3-Carboxamide CAS NO 924824-35-1 is a high-purity, advanced pharmaceutical intermediate characterized by its unique molecular architecture combining a chromene and a substituted thiazole moiety. This compound is of significant commercial interest for its role in the research and development of novel therapeutic agents, particularly in oncology and metabolic disease pathways. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the synthesis of complex bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, especially kinase inhibitors.
• Biochemical Research: Used as a reference standard or a probe molecule in enzymatic assays and target validation studies.
• Medicinal Chemistry: A key scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and cGMP production.
• Academic Research: Utilized in university and institutional labs for exploratory research in chemical biology and new therapeutic modalities.

Basic Information

Product Name	n-[5-(4-Chlorobenzyl)-1,3-Thiazol-2-Yl]-3,4-Dihydro-2H-Chromene-3-Carboxamide
CAS No.	924824-35-1
Molecular Formula	C21H19ClN2O2S
Molecular Weight	398.90 g/mol
Synonyms	N-[5-[(4-Chlorophenyl)methyl]-1,3-thiazol-2-yl]-3,4-dihydro-2H-1-benzopyran-3-carboxamide; 3,4-Dihydro-2H-1-benzopyran-3-carboxamide, N-[5-[(4-chlorophenyl)methyl]-2-thiazolyl]-; 924824-35-1; Chromene-3-carboxamide, N-[5-(4-chlorobenzyl)-1,3-thiazol-2-yl]-3,4-dihydro-2H-; 2H-Chromene-3-carboxamide, N-[5-[(4-chlorophenyl)methyl]-2-thiazolyl]-3,4-dihydro-
EINECS	Contact for details

Quality Control

Our n-[5-(4-Chlorobenzyl)-1,3-Thiazol-2-Yl]-3,4-Dihydro-2H-Chromene-3-Carboxamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to ISO 9001 standards, and we support development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive (store away from light) and hygroscopic (moisture-sensitive). For long-term storage, consider desiccation and an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.