Description

4-[(6,7-Dimethoxy-3,4-Dihydro-1H-Isoquinoline-2-Carbonyl)-Amino]-Benzoic Acid is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of complex active pharmaceutical ingredients (APIs). This compound is valued for its role as a key building block in medicinal chemistry, particularly in the development of novel therapeutic agents targeting the central nervous system and cardiovascular diseases. It is primarily utilized by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers requiring precise molecular scaffolds for drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of tetrahydroisoquinoline-based active pharmaceutical ingredients (APIs).
• Drug Discovery & Medicinal Chemistry: Serves as a versatile building block for constructing novel chemical libraries and lead compounds in R&D.
• Neurological & Cardiovascular Research: Used in the development of potential therapeutics targeting specific receptors and enzymes involved in CNS and cardiovascular pathways.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale manufacturing of candidate drugs.
• Biochemical Research: May be used as a tool compound or ligand in biochemical assays and pharmacological studies.
• Contract Manufacturing (CMO/CDMO): Supplied to contract manufacturing organizations for the production of clinical trial materials and commercial APIs.

Basic Information

Item	Details
Product Name	4-[(6,7-Dimethoxy-3,4-Dihydro-1H-Isoquinoline-2-Carbonyl)-Amino]-Benzoic Acid
CAS No.	924779-19-1
Molecular Formula	C19H20N2O5
Molecular Weight	356.38 g/mol
Synonyms	4-[(6,7-Dimethoxy-3,4-dihydro-1H-isoquinoline-2-carbonyl)amino]benzoic acid; 4-[(6,7-Dimethoxy-1,2,3,4-tetrahydroisoquinoline-2-carbonyl)amino]benzoic acid; 4-[(6,7-Dimethoxy-3,4-dihydroisoquinoline-2(1H)-carbonyl)amino]benzoic acid; 4-(6,7-Dimethoxy-3,4-dihydro-1H-isoquinoline-2-carboxamido)benzoic acid; 924779-19-1; Benzoic acid, 4-[[(6,7-dimethoxy-3,4-dihydro-1H-isoquinoline-2-yl)carbonyl]amino]-
EINECS	Contact for details

Quality Control

Our 4-[(6,7-Dimethoxy-3,4-Dihydro-1H-Isoquinoline-2-Carbonyl)-Amino]-Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed chromatographic data (HPLC) are provided for every shipment, ensuring full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.