Description

1H-Indole, 3-[2-(3-Methyl-4-Nitro-5-Isoxazolyl)-1-Phenylethyl]- is a specialized, high-value synthetic organic compound featuring a complex molecular architecture that combines indole and isoxazole pharmacophores. This compound matters as a critical advanced pharmaceutical intermediate or research chemical for the development of novel bioactive molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries, where it serves as a key building block for creating new drug candidates and active ingredients.

Application

This complex heterocyclic compound is designed for sophisticated synthetic applications. Its primary and potential uses include:

• Pharmaceutical Intermediate: Serving as a crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new bioactive chemical space.
• Agrochemical Development: Acting as a precursor for novel pesticides or herbicides, leveraging the biological activity of the indole and nitroisoxazole motifs.
• Chemical Biology Probes: Utilized in academic and industrial research to study enzyme inhibition or protein-ligand interactions.
• Process Chemistry & Scale-up: Employed in route scouting and optimization for the commercial production of complex active pharmaceutical ingredients (APIs).

Basic Information

Product Name	1H-Indole, 3-[2-(3-Methyl-4-Nitro-5-Isoxazolyl)-1-Phenylethyl]-
CAS No.	924650-65-7
Molecular Formula	C20H17N3O3
Molecular Weight	347.37 g/mol
Synonyms	3-[2-(3-Methyl-4-nitro-5-isoxazolyl)-1-phenylethyl]-1H-indole; 1H-Indole-3-[2'-(3'-methyl-4'-nitro-5'-isoxazolyl)-1'-phenylethane]; (3-Methyl-4-nitro-5-isoxazolyl)(phenyl)ethyl indole; Indole derivative CAS 924650-65-7; Advanced indole-isoxazole hybrid; Nitroisoxazole-indole conjugate
EINECS	Contact for details

Quality Control

We supply this high-purity intermediate under a rigorous quality management system. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and MS to ensure structural identity and purity. A comprehensive Certificate of Analysis (COA) detailing purity, impurity profile, and physical data is provided with every shipment. Our production adheres to cGMP principles where applicable, ensuring traceability and consistency for critical R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent potential degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.