Description

2-Bromo-5-(Difluoromethyl)Thiophene is a high-value, multi-functional halogenated thiophene derivative. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block in modern organic synthesis. It is primarily sought after by R&D and production teams in the pharmaceutical, agrochemical, and material science industries for constructing complex molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in drug discovery programs targeting novel therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, such as herbicides and fungicides, leveraging the thiophene and fluorine motifs.
• Material Science Precursor: Serves as a monomer or precursor for the development of specialty polymers, conductive materials, and organic electronic components.
• Ligand & Catalyst Development: Employed in the creation of novel ligands and organocatalysts for asymmetric synthesis and cross-coupling reactions.
• Chemical Research (R&D): A versatile reagent for academic and industrial research in heterocyclic and fluorine chemistry, enabling structural diversification.
• Fluorine-Containing Compound Synthesis: Provides a difluoromethyl group source for introducing this metabolically stable and lipophilic moiety into target molecules.

Basic Information

Product Name	2-Bromo-5-(Difluoromethyl)Thiophene
CAS No.	924646-90-2
Molecular Formula	C5H3BrF2S
Molecular Weight	212.04 g/mol
Synonyms	2-Bromo-5-(difluoromethyl)thiophene; 5-(Difluoromethyl)-2-bromothiophene; Thiophene, 2-bromo-5-(difluoromethyl)-; 2-Bromo-5-difluoromethylthiophene; 924646-90-2; 2-Bromo-5-(difluoromethyl)thiophene, 97%; 2-Bromo-5-(difluoromethyl)-thiophene
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-(Difluoromethyl)Thiophene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and storage should minimize exposure to direct light.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.