Description

Benzo[D][1,3]Dioxol-(2,2-D2)-5-Ol CAS NO 923932-05-2 is a deuterated derivative of sesamol, featuring two deuterium atoms at the 2-position of the 1,3-dioxole ring. This isotopic labeling makes it a critical tool compound for research in pharmacokinetics, metabolic studies, and as an internal standard for quantitative mass spectrometry analysis. It is primarily utilized by pharmaceutical R&D laboratories, analytical chemistry service providers, and manufacturers of high-purity reference standards.

Application

• Internal standard for the precise quantification of sesamol and related compounds via GC-MS or LC-MS.
• Deuterated tracer in drug metabolism and pharmacokinetic (DMPK) studies to investigate absorption, distribution, metabolism, and excretion (ADME).
• Key intermediate in the synthesis of deuterium-labeled pharmaceuticals and bioactive molecules for research.
• Stable isotope-labeled reference material for analytical method development and validation in quality control laboratories.
• Probe molecule in mechanistic studies of antioxidant activity and reaction pathways.
• Component in the preparation of calibration standards for food, cosmetic, or nutraceutical analysis where sesamol is a marker.

Basic Information

Item	Detail
Product Name	Benzo[D][1,3]Dioxol-(2,2-D2)-5-Ol
CAS No.	923932-05-2
Molecular Formula	C7H4D2O3
Molecular Weight	140.14 g/mol
Synonyms	3,4-(Methylenedioxy)phenol-2,2-d2; Sesamol-2,2-d2; 5-Hydroxy-1,3-benzodioxole-2,2-d2; 1,3-Benzodioxol-5-ol-2,2-d2; 3,4-Methylenedioxyphenol-2,2-d2; Deuterated Sesamol; [2,2-D2]-Sesamol
EINECS	Contact for details

Quality Control

Our Benzo[D][1,3]Dioxol-(2,2-D2)-5-Ol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including NMR and Mass Spectrometry for isotopic enrichment and structural confirmation, and HPLC for chemical purity assessment. Certificates of Analysis (COA) detailing batch-specific results for identity, purity, and isotopic purity are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive); ensure the container is sealed under an inert atmosphere after opening to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (MS)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity (D-content)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.