Description

3-(3,4-Dihydroisoquinolin-2(1H)-Ylsulfonyl)Benzonitrile is a high-purity organic chemical building block featuring a unique dihydroisoquinoline scaffold linked to a benzonitrile moiety via a sulfonyl group. This compound is valued for its role as a versatile synthetic intermediate in advanced pharmaceutical research and fine chemical synthesis. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure.
• Chemical Biology Probe: Serves as a precursor for designing molecular probes to study enzyme function and biological pathways.
• Material Science: Potential monomer or additive in the development of advanced polymers with specific electronic or optical properties.
• Academic & Contract Research: Essential reagent for methodological development and synthetic chemistry studies in academic and CRO (Contract Research Organization) laboratories.

Basic Information

Product Name	3-(3,4-Dihydroisoquinolin-2(1H)-Ylsulfonyl)Benzonitrile
CAS No.	923836-09-3
Molecular Formula	C₁₆H₁₂N₂O₂S
Molecular Weight	296.35 g/mol
Synonyms	3-[(3,4-Dihydro-1H-isoquinolin-2-yl)sulfonyl]benzonitrile; 2-(3-Cyanophenylsulfonyl)-1,2,3,4-tetrahydroisoquinoline; 3-(1,2,3,4-Tetrahydroisoquinoline-2-sulfonyl)benzonitrile; Benzonitrile, 3-[(3,4-dihydro-1H-isoquinolin-2-yl)sulfonyl]-; 923836-09-3; 3-(3,4-Dihydroisoquinolin-2(1H)-ylsulfonyl)benzonitrile; 3-(2,3-Dihydro-1H-isoquinolin-2-ylsulfonyl)benzonitrile
EINECS	Contact for details

Quality Control

Our 3-(3,4-Dihydroisoquinolin-2(1H)-Ylsulfonyl)Benzonitrile is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical data is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.