Description

5-(4-(Trifluoromethyl)Benzyl)Thiazol-2-Amine is a high-value, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. Its core value lies in the unique combination of the electron-withdrawing trifluoromethyl group and the versatile thiazole-2-amine scaffold, which is crucial for modulating the physicochemical and biological properties of target molecules. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the discovery and development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly in areas like kinase inhibitors, anti-infectives, and central nervous system (CNS) agents.
• Agrochemical Synthesis: Used in constructing advanced herbicides, fungicides, and insecticides where the CF3 group enhances lipophilicity and metabolic stability.
• Material Science Research: Serves as a precursor for specialty chemicals, ligands, or monomers in the development of advanced polymers and functional materials.
• Chemical Biology & Proteomics: Employed as a molecular scaffold or a tagging reagent in probe development for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring the introduction of a specific fluorinated benzyl-thiazole motif.

Basic Information

Product Name	5-(4-(Trifluoromethyl)Benzyl)Thiazol-2-Amine
CAS No.	923813-54-1
Molecular Formula	C11H9F3N2S
Molecular Weight	258.26 g/mol
Synonyms	2-Amino-5-[(4-(trifluoromethyl)phenyl)methyl]-1,3-thiazole; 5-[(4-(Trifluoromethyl)phenyl)methyl]-1,3-thiazol-2-amine; 5-[(4-Trifluoromethylbenzyl)]thiazol-2-ylamine; 2-Thiazolamine, 5-[[4-(trifluoromethyl)phenyl]methyl]-; α-(2-Aminothiazol-5-ylmethyl)-4-(trifluoromethyl)benzene
EINECS	Contact for details

Quality Control

Our 5-(4-(Trifluoromethyl)Benzyl)Thiazol-2-Amine is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR, MS), to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.