Description

3-(Piperidin-1-Ylsulfonyl)Thiophene-2-Carboxylic Acid is a high-purity, functionalized heterocyclic building block of significant interest in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals, where its unique sulfonamide-thiophene scaffold is highly valuable. Pharmaceutical researchers, agrochemical developers, and specialty chemical manufacturers need this precise chemical to drive innovation in drug discovery and crop protection programs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of potential drug candidates, particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its bioactive heterocyclic structure.
• Chemical Biology & Proteomics: Serves as a versatile scaffold for designing chemical probes and activity-based protein profiling (ABPP) reagents.
• Material Science Precursor: Can be utilized in the synthesis of functionalized polymers or organic electronic materials due to its conjugated thiophene system.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthetic routes.
• Academic & Institutional Research: Used in universities and research institutes for methodological studies in organic chemistry and medicinal chemistry.

Basic Information

Product Name	3-(Piperidin-1-Ylsulfonyl)Thiophene-2-Carboxylic Acid
CAS No.	923697-76-1
Molecular Formula	C11H15NO4S2
Molecular Weight	289.37 g/mol
Synonyms	3-(1-Piperidinosulfonyl)thiophene-2-carboxylic acid; 2-Thiophenecarboxylic acid, 3-(1-piperidinosulfonyl)-; 3-(Piperidine-1-sulfonyl)thiophene-2-carboxylic acid; Thiophene-2-carboxylic acid, 3-(piperidin-1-ylsulfonyl)-; 923697-76-1; 3-Piperidin-1-ylsulfonyl-thiophene-2-carboxylic acid
EINECS	Contact for details

Quality Control

Our 3-(Piperidin-1-Ylsulfonyl)Thiophene-2-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical characterization, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or cGMP guidelines for early-phase development. We are committed to supplying material that meets the high standards required for pharmaceutical R&D.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound is compatible with strong acid/organic solvent environments but should be kept separate from strong bases and oxidizing agents. For long-term storage, consider using desiccants to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.