Description

2-[(2-Chloropropanoyl)Amino]-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxamide is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound matters because it provides a critical, structurally complex building block essential for research and development in modern medicinal chemistry. Pharmaceutical companies and contract research organizations (CROs) need this precise intermediate to develop new therapeutic agents, particularly in areas targeting specific enzymatic pathways.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of new drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize lead compounds for potency and selectivity.
• API Synthesis: Serves as a core scaffold in the multi-step synthesis of complex target molecules for preclinical testing.
• Biochemical Tool Compound: Potential use in biochemical assays to study and modulate specific biological targets.
• Contract Manufacturing: Supplied to CDMOs for the cGMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for cutting-edge organic synthesis and drug discovery projects.

Basic Information

Product Name	2-[(2-Chloropropanoyl)Amino]-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxamide
CAS No.	923206-07-9
Molecular Formula	C13H15ClN2O2S
Molecular Weight	298.79 g/mol
Synonyms	2-[(2-Chloropropanoyl)amino]-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxamide; 2-(2-Chloropropanamido)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide; 923206-07-9; 2-(2-Chloropropanoylamino)-5,6-dihydro-4H-cyclopenta[b]thiophene-3-carboxylic acid amide; Cyclopenta[b]thiophene-3-carboxamide, 2-[(2-chloro-1-oxopropyl)amino]-4,5,6,7-tetrahydro-; AMG-208 Intermediate (related compound)
EINECS	Contact for details

Quality Control

Our 2-[(2-Chloropropanoyl)Amino]-5,6-Dihydro-4H-Cyclopenta[B]Thiophene-3-Carboxamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.