Description

4B,5,6,7,8,8A-Hexahydropyrido[4',3':4,5]Thieno[2,3-D]Pyrimidin-4-Amine is a high-purity, advanced pharmaceutical intermediate with the CAS number 923133-15-7. This heterocyclic compound is a critical building block in modern medicinal chemistry, enabling the synthesis of complex, biologically active molecules. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in the development of novel therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of targeted small-molecule drugs.
• Oncology Research: Used in the development of kinase inhibitors and other anti-cancer compounds.
• CNS Drug Discovery: Serves as a scaffold for potential neuropharmaceuticals targeting specific receptors.
• Medicinal Chemistry R&D: Employed in structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Utilized in route scouting and scale-up for active pharmaceutical ingredient (API) manufacturing.
• Contract Research & Manufacturing (CRO/CMO): Supplied to service organizations supporting global drug development programs.

Basic Information

Item	Detail
Product Name	4B,5,6,7,8,8A-Hexahydropyrido[4',3':4,5]Thieno[2,3-D]Pyrimidin-4-Amine
CAS No.	923133-15-7
Molecular Formula	C10H14N4S
Molecular Weight	222.31 g/mol
Synonyms	4-Amino-4b,5,6,7,8,8a-hexahydro-4H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidine; Hexahydropyridothienopyrimidin-4-amine; 923133-15-7; 4-Amino-4b,5,6,7,8,8a-hexahydro-4H-pyrido[4',3':4,5]thieno[2,3-d]pyrimidine; 4H-Pyrido[4',3':4,5]thieno[2,3-d]pyrimidin-4-amine, 4b,5,6,7,8,8a-hexahydro-; Thienopyrimidine derivative CAS 923133-15-7
EINECS	Contact for details

Quality Control

Our 4B,5,6,7,8,8A-Hexahydropyrido[4',3':4,5]Thieno[2,3-D]Pyrimidin-4-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) detailing batch-specific results are provided and can be tailored to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere when appropriate to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.