Description

4-Chloro-2-(Dimethylamino)-1,3-Thiazole-5-Carbaldehyde is a versatile and highly functionalized heterocyclic building block. This compound is critical for the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, due to its reactive aldehyde and halogenated thiazole core. It is primarily sought after by research chemists and process development scientists engaged in medicinal chemistry and fine chemical manufacturing.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, especially those targeting infectious diseases or acting as kinase inhibitors.
• Agrochemical Synthesis: Building block for developing advanced fungicides, herbicides, and insecticides with specific modes of action.
• Material Science Research: Used in the creation of specialized ligands, catalysts, and functional organic materials.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the production of bespoke compounds and active pharmaceutical ingredients (APIs).

Basic Information

Product Name	4-Chloro-2-(Dimethylamino)-1,3-Thiazole-5-Carbaldehyde
CAS No.	923130-57-8
Molecular Formula	C6H7ClN2OS
Molecular Weight	190.65 g/mol
Synonyms	4-Chloro-2-(dimethylamino)-1,3-thiazole-5-carboxaldehyde; 5-Formyl-4-chloro-2-(dimethylamino)thiazole; 2-(Dimethylamino)-4-chloro-1,3-thiazole-5-carbaldehyde; 4-Chloro-2-(N,N-dimethylamino)thiazole-5-carbaldehyde; 923130-57-8; 4-Chloro-2-dimethylaminothiazole-5-carboxaldehyde
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-(Dimethylamino)-1,3-Thiazole-5-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.