Description

Ethyl 4,5-Dimethyl-2-{[(5-Methyl-1-Phenyl-1H-1,2,3-Triazol-4-Yl)Carbonyl]Amino}Thiophene-3-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique molecular architecture combining thiophene and triazole heterocycles. This compound matters for its critical role as a specialized building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular design. Pharmaceutical R&D laboratories and fine chemical manufacturers need this precise intermediate to develop next-generation drug candidates with potential applications in oncology, anti-inflammatory, and antiviral research.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the research and development of new chemical entities (NCEs) and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Heterocyclic Compound Synthesis: Acts as a versatile scaffold for constructing complex molecules containing fused thiophene-triazole systems.
• Bioconjugation & Probe Development: Potential utility in creating labeled compounds or molecular probes for biochemical and diagnostic applications.
• Agrochemical Research: Investigated as an intermediate for developing novel crop protection agents with specific modes of action.
• Material Science Precursor: Explored for the synthesis of specialized organic electronic materials or ligands for catalysis.

Basic Information

Product Name	Ethyl 4,5-Dimethyl-2-{[(5-Methyl-1-Phenyl-1H-1,2,3-Triazol-4-Yl)Carbonyl]Amino}Thiophene-3-Carboxylate
CAS No.	923113-37-5
Molecular Formula	C20H21N5O3S
Molecular Weight	411.48 g/mol
Synonyms	Ethyl 4,5-dimethyl-2-[[(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)carbonyl]amino]thiophene-3-carboxylate; 923113-37-5; 4,5-Dimethyl-2-({[5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl]carbonyl}amino)thiophene-3-carboxylic acid ethyl ester; Thiophene-3-carboxylic acid, 2-[[(5-methyl-1-phenyl-1H-1,2,3-triazol-4-yl)carbonyl]amino]-4,5-dimethyl-, ethyl ester; AKOS025247315; AS-76379; ZINC000253849911
EINECS	Contact for details

Quality Control

Our Ethyl 4,5-Dimethyl-2-{[(5-Methyl-1-Phenyl-1H-1,2,3-Triazol-4-Yl)Carbonyl]Amino}Thiophene-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to minimize exposure to moisture. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.