Description

2-Amino-5-(4-Fluorophenyl)-1,3-Thiazole-4-Carboxylic Acid is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a critical intermediate for constructing complex molecules with tailored biological and material properties. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for applications in drug discovery, agrochemical development, and materials science.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and anti-inflammatory drug candidates.
• Agrochemical Research: Serves as a core structure for designing new herbicides, fungicides, and insecticides, leveraging the bioactivity of the thiazole and fluorophenyl moieties.
• Material Science Precursor: Used in the synthesis of specialized ligands, dyes, and photoactive compounds for advanced material applications.
• Chemical Biology Probe: Employed in medicinal chemistry to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis Building Block: Supplied to contract research organizations (CROs) and CDMOs for bespoke synthesis projects requiring fluorinated heterocycles.

Basic Information

Product Name	2-Amino-5-(4-Fluorophenyl)-1,3-Thiazole-4-Carboxylic Acid
CAS No.	923106-11-0
Molecular Formula	C10H7FN2O2S
Molecular Weight	238.24 g/mol
Synonyms	4-Fluorophenyl-2-aminothiazole-5-carboxylic Acid; 2-Amino-5-(4-fluorophenyl)-1,3-thiazole-4-carboxylic acid; 5-(4-Fluorophenyl)-2-amino-1,3-thiazole-4-carboxylic Acid; 4-Carboxy-2-amino-5-(4-fluorophenyl)thiazole; 923106-11-0; 2-Amino-5-(p-fluorophenyl)-4-thiazolecarboxylic acid
EINECS	Contact for details

Quality Control

Our 2-Amino-5-(4-Fluorophenyl)-1,3-Thiazole-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results. We support development and commercial projects requiring material meeting GMP or other stringent regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the original container tightly sealed under an inert atmosphere if possible. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.