Description

(R)-1-(3,4,5-Trifluorophenyl)Ethanol is a high-value chiral intermediate characterized by its trifluoromethylphenyl backbone and specific (R)-enantiomeric configuration. This compound is critical for imparting metabolic stability and enhancing lipophilicity in advanced pharmaceutical molecules. It is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral drug discovery.
• Agrochemical Synthesis: Used in the research and development of advanced herbicides and pesticides, where the fluorine atoms contribute to biological activity and environmental persistence.
• Liquid Crystal Materials: Serves as a precursor in the production of fluorine-containing liquid crystals for display technologies.
• Asymmetric Catalysis: Employed as a chiral ligand or auxiliary in stereoselective synthesis to control the formation of specific enantiomers.
• Organic Electronic Materials: A potential monomer or intermediate for developing novel organic semiconductors and electronic materials.
• Chemical Research & Development: Used in academic and industrial R&D for exploring new synthetic methodologies and creating compound libraries.

Basic Information

Product Name	(R)-1-(3,4,5-Trifluorophenyl)Ethanol
CAS No.	923033-01-6
Molecular Formula	C8H7F3O
Molecular Weight	182.14 g/mol
Synonyms	(R)-1-(3,4,5-Trifluorophenyl)ethan-1-ol; (R)-α-(3,4,5-Trifluorophenyl)ethyl alcohol; (R)-3,4,5-Trifluoro-α-methylbenzyl alcohol; (R)-1-(3,4,5-Trifluorophenyl)ethyl alcohol; (R)-TFPE; (R)-TFE; (R)-1-(Perfluorophenyl)ethanol (common misnomer)
EINECS	Contact for details

Quality Control

Our (R)-1-(3,4,5-Trifluorophenyl)Ethanol is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and optical purity suitable for sensitive synthetic applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent oxidation or degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.