Description

7-Bromo-6-Fluoro-1,2-Dihydroisoquinolin-1-One is a high-purity, advanced pharmaceutical intermediate with a distinct halogenated isoquinolinone structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of complex molecules with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and oncology-related drug discovery programs.

Application

• Pharmaceutical Intermediate: A key synthon in the multi-step synthesis of novel drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• API Development: Serves as a core scaffold for constructing complex heterocyclic systems found in potential therapeutic agents.
• Chemical Biology Probes: Utilized in the development of molecular probes for studying enzyme function and biological pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Product Name	7-Bromo-6-Fluoro-1,2-Dihydroisoquinolin-1-One
CAS No.	923022-43-9
Molecular Formula	C9H5BrFNO
Molecular Weight	242.05 g/mol
Synonyms	7-Bromo-6-fluoro-3,4-dihydro-1H-isoquinolin-1-one; 7-Bromo-6-fluoro-1,2-dihydroisoquinolin-1-one; 1H-Isoquinolin-1-one, 7-bromo-6-fluoro-3,4-dihydro-; 923022-43-9; 7-Bromo-6-fluoro-3,4-dihydroisoquinolin-1(2H)-one; 7-Bromo-6-fluoro-1,2-dihydro-isoquinolin-1-one
EINECS	Contact for details

Quality Control

Our 7-Bromo-6-Fluoro-1,2-Dihydroisoquinolin-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for pharmaceutical R&D, ensuring reliable and consistent performance in your synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.