Description

7-Bromo-6-Fluoroisoquinoline is a high-purity halogenated isoquinoline derivative, a crucial advanced intermediate in modern synthetic chemistry. Its value lies in its unique molecular scaffold, which serves as a versatile building block for constructing complex, biologically active molecules. This compound is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs), agrochemicals, and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in kinase inhibitor and anticancer agent research.
• Agrochemical Development: Used as a core structure for creating new herbicides, fungicides, and pesticides with enhanced efficacy.
• Material Science Research: Serves as a precursor for organic light-emitting diodes (OLEDs) and other electronic materials due to the isoquinoline core.
• Ligand and Catalyst Synthesis: Employed in the preparation of specialized ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probes: Utilized to develop fluorescent tags and molecular probes for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke synthesis projects.

Basic Information

Product Name	7-Bromo-6-Fluoroisoquinoline
CAS No.	923022-40-6
Molecular Formula	C9H5BrFN
Molecular Weight	226.05 g/mol
Synonyms	6-Fluoro-7-bromoisoquinoline; Isoquinoline, 7-bromo-6-fluoro-; 7-Bromo-6-fluoro-isoquinoline; 923022-40-6; 6-Fluoro-7-bromo-isoquinoline; 7-Bromo-6-fluoroisoquinoline; 7-Br-6-F-isoquinoline
EINECS	Contact for details

Quality Control

Our 7-Bromo-6-Fluoroisoquinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.