Description

2-Amino-6-(tert-Butoxycarbonyl)-4,5,6,7-Tetrahydrothieno[2,3-C]Pyridine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure with both amino and carboxylic acid functional groups protected by a tert-butoxycarbonyl (Boc) moiety. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other targeted therapeutics. It is primarily sought after by research institutions and pharmaceutical companies engaged in drug discovery and process chemistry for central nervous system (CNS) and oncological applications.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, especially kinase inhibitors and other small molecule therapeutics.
• Drug Discovery & Research: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in preclinical research.
• Process Chemistry Development: Serves as a critical starting material or intermediate in scaling up synthetic routes for new chemical entities (NCEs).
• Protease Inhibitor Synthesis: Potential application in the construction of molecules targeting specific enzymatic pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules.
• Academic Research: Utilized in university and institutional labs for the study of heterocyclic chemistry and novel organic transformations.

Basic Information

Product Name	2-Amino-6-(tert-Butoxycarbonyl)-4,5,6,7-Tetrahydrothieno[2,3-C]Pyridine-3-Carboxylic Acid
CAS No.	923010-68-8
Molecular Formula	C13H18N2O4S
Molecular Weight	298.36 g/mol
Synonyms	2-Amino-6-Boc-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic acid; 6-(tert-Butoxycarbonyl)-2-amino-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic acid; 2-Amino-6-(Boc)-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic acid; Boc-protected thienopyridine carboxylic acid; CAS 923010-68-8; 6-Boc-2-amino-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylic acid; 3-Carboxy-2-amino-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-6-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 2-Amino-6-(tert-Butoxycarbonyl)-4,5,6,7-Tetrahydrothieno[2,3-C]Pyridine-3-Carboxylic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen) for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.