Description

3,4-Dimethoxy-2-Methylpyridine n-Oxide-D3 is a deuterated derivative of a pyridine N-oxide, specifically labeled with three deuterium atoms. This compound is a crucial stable isotope-labeled building block used in advanced research and development, particularly in the fields of pharmaceutical and agrochemical discovery. It serves as a key intermediate for the synthesis of deuterated active pharmaceutical ingredients (APIs) and other fine chemicals, enabling metabolic and pharmacokinetic studies. Industries requiring high-purity, specialized intermediates for drug development and analytical standards will find this product essential.

Application

• Pharmaceutical Research & Development: As a deuterated intermediate for synthesizing novel Active Pharmaceutical Ingredients (APIs) in drug discovery programs.
• Metabolic Studies: Used as an internal standard or tracer in mass spectrometry and NMR for studying drug metabolism and pharmacokinetics (DMPK).
• Agrochemical Development: Serves as a building block for creating deuterated versions of agrochemicals to study their environmental fate and efficacy.
• Material Science: Potential use in the synthesis of advanced organic materials and ligands for catalysis where isotopic labeling is beneficial.
• Analytical Standards: Manufacture of certified reference materials (CRMs) for precise quantitative analysis in regulatory and quality control laboratories.

Basic Information

Item	Details
Product Name	3,4-Dimethoxy-2-Methylpyridine n-Oxide-D3
CAS No.	922727-41-1
Molecular Formula	C8H8D3NO3
Molecular Weight	~170.19 g/mol
Synonyms	2-Methyl-3,4-dimethoxypyridine 1-Oxide-d3; 3,4-Dimethoxy-2-methylpyridine N-oxide-d3; Deuterated 3,4-Dimethoxy-2-methylpyridine N-oxide; 2-Methyl-3,4-dimethoxypyridine-d3 N-oxide; Pyridine-d3, 3,4-dimethoxy-2-methyl-, 1-oxide; 3,4-Dimethoxy-2-methyl-1-oxidopyridin-1-ium-d3; (2-Methyl-3,4-dimethoxypyridin-1-ium-1-olate)-d3
EINECS	Contact for details

Quality Control

Our 3,4-Dimethoxy-2-Methylpyridine n-Oxide-D3 is manufactured under strict quality systems to ensure high chemical and isotopic purity, meeting the rigorous demands of research and development. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing parameters such as assay (by HPLC or NMR), deuterium enrichment, and impurity profile. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR / NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.