Description

Chloroform-D CAS NO 865-49-6 is a deuterated isotopologue of chloroform, where the hydrogen atom is replaced by deuterium, a stable hydrogen isotope. This isotopic labeling is critical for applications requiring minimal spectral interference, particularly in nuclear magnetic resonance (NMR) spectroscopy. It is an essential solvent and analytical standard for research and quality control laboratories in the pharmaceutical, chemical, and academic sectors.

Application

• NMR Spectroscopy: Primary use as a deuterated solvent for proton NMR, providing a lock signal and a non-interfering background for analyzing organic compounds.
• Analytical Standard: Serves as a certified reference material (CRM) for instrument calibration, method validation, and quantitative analysis.
• Chemical Synthesis: Used as a deuterium source or solvent in synthetic chemistry for preparing labeled compounds in pharmaceutical and metabolic research.
• Pharmaceutical Research: Employed in drug discovery and development for studying molecular structures, reaction mechanisms, and metabolic pathways.
• Academic & Industrial R&D: A fundamental reagent in university and corporate research laboratories for a wide range of experimental procedures.
• Quality Control (QC) Labs: Utilized in pharmaceutical and chemical industry QC protocols to ensure product purity and consistency.

Basic Information

Product Name	Chloroform-D
CAS No.	865-49-6
Molecular Formula	CDCl3
Molecular Weight	120.38 g/mol
Synonyms	Deuterochloroform; Chloroform-d; Trichloro(deuterio)methane; Deuterated Chloroform; CDCl3; NMR Solvent Chloroform-d; Chloroform-D1; Deuteriochloroform
EINECS	212-742-2

Quality Control

Our Chloroform-D is produced and tested under stringent quality management systems. Each batch is analyzed to meet high-purity standards suitable for sensitive spectroscopic and synthetic applications. A comprehensive Certificate of Analysis (COA) detailing isotopic purity, chemical purity, and specific tests is provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Clear, colorless liquid
Identification (IR)	Conforms
Deuterium Content (NMR)	≥ 99.8 atom % D
Assay (GC)	≥ 99.9%
Water (Karl Fischer)	≤ 0.05%
Residue after Evaporation	≤ 0.001%
UV Absorbance	Conforms to spectroscopic grade

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.