Description

R-3,3'-Bis(2-Naphthyl)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Binaphthyl-2,2'-Diyl Hydrogenphosphate is a sophisticated chiral organophosphorus compound, serving as a high-performance ligand and catalyst precursor in asymmetric synthesis. Its value lies in its ability to induce high enantioselectivity in critical carbon-carbon and carbon-heteroatom bond-forming reactions, which is paramount for producing single-enantiomer active pharmaceutical ingredients (APIs) and fine chemicals. This product is essential for R&D and production chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity chiral auxiliaries to develop novel therapeutics and specialty compounds.

Application

• As a chiral ligand for transition metal-catalyzed asymmetric hydrogenation and transfer hydrogenation reactions.
• As a catalyst precursor in enantioselective C-C cross-coupling reactions (e.g., Suzuki-Miyaura, Heck reactions).
• Utilized in the asymmetric synthesis of key intermediates for blockbuster pharmaceuticals, including antivirals and cardiovascular drugs.
• Employed in the development of novel agrochemicals, such as herbicides and fungicides, with improved efficacy and environmental profiles.
• As a resolving agent or chiral selector in the purification of enantiomers via crystallization or chromatography.
• In academic and industrial research for developing new methodologies in stereoselective synthesis.
• Potential use in the synthesis of chiral functional materials, including liquid crystals and polymers.

Basic Information

Product Name	R-3,3'-Bis(2-Naphthyl)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Binaphthyl-2,2'-Diyl Hydrogenphosphate
CAS No.	922711-75-9
Molecular Formula	C44H35O4P
Molecular Weight	658.72 g/mol
Synonyms	(R)-3,3'-Bis(2-naphthyl)-5,5',6,6',7,7',8,8'-octahydro-1,1'-binaphthyl-2,2'-diyl hydrogenphosphate; (R)-3,3'-Di(2-naphthyl)-H8-BINOL phosphate; (R)-H8-BINOL-3,3'-di(2-naphthyl) phosphate; R-3,3'-Bis(2-naphthyl)-H8-BINAP phosphate; R-3,3'-Dinaphthyl-H8-BINOL phosphate; (R)-3,3'-Bis(2-naphthyl)-H8-1,1'-Bi-2-naphthol hydrogen phosphate; Chiral binaphthyl phosphate ligand; (R)-H8-BINOL derivative phosphate
EINECS	Contact for details

Quality Control

Our R-3,3'-Bis(2-Naphthyl)-5,5',6,6',7,7',8,8'-Octahydro-1,1'-Binaphthyl-2,2'-Diyl Hydrogenphosphate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and optical purity suitable for demanding catalytic applications. Comprehensive Certificates of Analysis (COA) detailing purity, identity, and chiral purity are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain optimal stability and performance.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.