Description

1-Phenanthrol-D9 is a deuterium-labeled derivative of 1-phenanthrol, a key compound in advanced analytical chemistry. This isotopically labeled standard is essential for ensuring accuracy and reliability in quantitative mass spectrometry, serving as a critical internal reference. It is primarily used by researchers and quality control laboratories in the pharmaceutical, environmental, and forensic science sectors for precise metabolite tracking, method validation, and complex mixture analysis.

Application

• Internal Standard for LC-MS/MS: Used as a quantitative reference standard in liquid chromatography-tandem mass spectrometry for the analysis of polycyclic aromatic hydrocarbon (PAH) metabolites and related compounds.
• Pharmaceutical Research: Facilitates drug metabolism and pharmacokinetics (DMPK) studies by enabling the accurate measurement of phenanthrene-derived metabolites in biological matrices.
• Environmental Monitoring: Critical for the precise quantification of PAH exposure biomarkers in human urine or environmental samples, supporting occupational health and pollution studies.
• Forensic Toxicology: Employed in method development and validation for the detection of specific toxins or their metabolic byproducts with high specificity.
• Stable Isotope Dilution Assays: Provides the foundation for highly accurate assays that correct for analyte loss during sample preparation and matrix effects.
• Biomarker Discovery & Validation: Supports research into new exposure biomarkers by allowing for precise, reproducible quantification in complex samples.

Basic Information

Product Name	1-Phenanthrol-D9
CAS No.	922510-23-4
Molecular Formula	C14H D9 O
Molecular Weight	~197.3 g/mol
Synonyms	1-Hydroxyphenanthrene-D9; Phenanthren-1-ol-D9; Deuterated 1-Phenanthrol; [D9]-1-Phenanthrol; 1-Phenanthrol (deuterated); 1-Phenanthrol-d9; Internal Standard for PAH Metabolites; Isotopically Labeled Phenanthrol
EINECS	Contact for details

Quality Control

Every batch of 1-Phenanthrol-D9 is manufactured and tested to meet the stringent requirements for isotopic purity and chemical integrity demanded by analytical laboratories. Our products undergo rigorous quality testing, including NMR and mass spectrometry, to ensure compliance with industry standards. Certificates of Analysis (COA) detailing isotopic enrichment (typically ≥98 atom % D), chemical purity (by HPLC), and identity confirmation are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. Keep the container in a cool, dry, and well-ventilated place. For long-term storage, solutions should be prepared in appropriate deuterated solvents and kept at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Isotopic Purity	≥98 atom % D
Chemical Purity	≥95%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.