Description

Methyl2-((1R,3R)-3-Amino-1-Hydroxy-4-Methylpentyl)Thiazole-4-Carboxylate CAS NO 921988-33-2 is a high-purity, chiral thiazole derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its defined stereochemistry and functional groups, which enable precise molecular construction in complex chemical pathways. It is primarily sought after by research institutions and pharmaceutical development teams for the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for complex target molecules.
• Organic Synthesis Building Block: Utilized in multi-step synthesis for constructing thiazole-containing heterocyclic compounds with specific stereocenters.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization processes within drug discovery programs.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes from laboratory to pilot plant scale.
• Bioconjugation & Probe Synthesis: Potential use in creating labeled compounds or molecular probes for biochemical and diagnostic applications.

Basic Information

Item	Details
Product Name	Methyl2-((1R,3R)-3-Amino-1-Hydroxy-4-Methylpentyl)Thiazole-4-Carboxylate
CAS No.	921988-33-2
Molecular Formula	C12H18N2O3S
Molecular Weight	270.35 g/mol
Synonyms	(1R,3R)-Methyl 3-Amino-1-hydroxy-4-methylpentyl-4-thiazolecarboxylate; (3R,5R)-5-[(4-Methoxycarbonyl-1,3-thiazol-2-yl)methyl]-3-methylpyrrolidin-2-one (tautomer); Methyl 2-[(1R,3R)-3-Amino-1-hydroxy-4-methylpentyl]-1,3-thiazole-4-carboxylate; 921988-33-2; Thiazole-4-carboxylic acid, 2-[(1R,3R)-3-amino-1-hydroxy-4-methylpentyl]-, methyl ester
EINECS	Contact for details

Quality Control

Our production of Methyl2-((1R,3R)-3-Amino-1-Hydroxy-4-Methylpentyl)Thiazole-4-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. All materials are characterized using advanced analytical techniques including HPLC, NMR, and chiral analysis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.