Description

1H-Indole-3-Carboxylic Acid,6-Chloro-,Methyl Ester is a high-value, halogenated indole derivative that serves as a critical synthetic intermediate in advanced organic chemistry. This compound matters for its role in constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for process development and scale-up activities.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting neurological and oncological pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and plant growth regulators due to its bioactive indole core.
• Organic Synthesis: Serves as a versatile precursor for further functionalization, enabling the creation of complex heterocyclic compounds.
• Biochemical Research: Employed in the study of enzyme inhibitors and receptor ligands as a scaffold for structure-activity relationship (SAR) studies.
• Material Science: Investigated as a monomer or additive for creating specialized polymers with unique optical or electronic properties.

Basic Information

Product Name	1H-Indole-3-Carboxylic Acid,6-Chloro-,Methyl Ester
CAS No.	921194-97-0
Molecular Formula	C10H8ClNO2
Molecular Weight	209.63 g/mol
Synonyms	6-Chloro-1H-indole-3-carboxylic acid methyl ester; Methyl 6-chloro-1H-indole-3-carboxylate; 6-Chloroindole-3-carboxylic acid methyl ester; 1H-Indole-3-carboxylic acid, 6-chloro-, methyl ester; 921194-97-0; Methyl 6-chloroindole-3-carboxylate; 6-Chloro-3-(methoxycarbonyl)-1H-indole
EINECS	Contact for details

Quality Control

Our 1H-Indole-3-Carboxylic Acid,6-Chloro-,Methyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with key parameters including assay (HPLC), related substances, and residual solvents. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliable supply for critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere if long-term storage is required to prevent potential degradation. Keep away from strong oxidizers and bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.