Description

tert-Butyl 3-Bromo-4-formyl-1H-indole-1-carboxylate is a high-purity, advanced pharmaceutical intermediate characterized by its strategically functionalized indole scaffold. This compound matters for its critical role as a versatile building block in the synthesis of complex bioactive molecules, particularly in medicinal chemistry. It is primarily needed by R&D scientists and process chemists in the pharmaceutical and agrochemical industries for developing new drug candidates and active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel indole-based drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization due to its reactive bromo and formyl functional groups.
• Agrochemical Synthesis: Serves as a precursor in the development of new crop protection agents and pesticides.
• Organic Synthesis: A versatile substrate for cross-coupling reactions (e.g., Suzuki, Sonogashira) and further derivatization to create diverse chemical libraries.
• Bioconjugation & Probe Development: Potential use in creating fluorescent probes or affinity labels for biochemical research.

Basic Information

Product Name	tert-Butyl 3-Bromo-4-formyl-1H-indole-1-carboxylate
CAS No.	921125-94-2
Molecular Formula	C14H14BrNO3
Molecular Weight	324.17 g/mol
Synonyms	1-Boc-3-bromo-4-formylindole; 3-Bromo-4-formyl-1H-indole-1-carboxylic acid tert-butyl ester; tert-Butyl 3-bromo-4-formylindole-1-carboxylate; 1H-Indole-1-carboxylic acid, 3-bromo-4-formyl-, 1,1-dimethylethyl ester; 3-Bromo-4-formylindole-1-N-Boc; Boc-3-Bromo-4-formylindole; 921125-94-2; 1-(tert-Butoxycarbonyl)-3-bromo-4-formylindole
EINECS	Contact for details

Quality Control

Our tert-Butyl 3-Bromo-4-formyl-1H-indole-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided to guarantee consistency and traceability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flames. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.