Description

9H-Purine-6-Ethanethiol is a specialized purine derivative functionalized with an ethanethiol side chain, serving as a critical building block in advanced organic synthesis. Its primary value lies in its role as a versatile intermediate for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for scientists and manufacturers in the life sciences sector, especially those focused on nucleoside chemistry, antiviral agents, and targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel nucleoside analogs and purine-based therapeutics.
• Antiviral Drug Research: Used in the development of potential antiviral compounds targeting viral replication mechanisms.
• Bioconjugation & Probe Development: The thiol group enables site-specific conjugation for creating biochemical probes and labeled compounds.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery.
• Biochemical Research: Employed in studies of enzyme inhibitors and purine metabolism pathways.
• Material Science: Potential use in creating functionalized surfaces or polymers via thiol-ene chemistry.

Basic Information

Product Name	9H-Purine-6-Ethanethiol
CAS No.	920503-84-0
Molecular Formula	C7H8N4S
Molecular Weight	180.23 g/mol
Synonyms	6-(2-Mercaptoethyl)purine; 6-(2-Thioethyl)purine; Purine-6-ethanethiol; 9H-Purine-6-ethanethiol; 6-(2-Sulfanylethyl)-9H-purine; 2-(9H-Purin-6-yl)ethanethiol; 6-(2-Mercaptoethyl)-9H-purine; 6-(2-Hydroxyethylthio)purine (related form)
EINECS	Contact for details

Quality Control

Our 9H-Purine-6-Ethanethiol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and spectroscopic methods (NMR, MS) for structural confirmation, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at 2-8°C to minimize oxidation and degradation. The material is easily oxidized (store under inert atmosphere). Keep the container in a cool, dry, and well-ventilated area, separate from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.