Description

n-[2-(5-Fluoro-1H-Indol-3-Yl)Ethyl]-2-(1H-Indol-3-Yl)Acetamide is a sophisticated bis-indole derivative of significant interest in advanced organic synthesis and pharmaceutical research. This compound matters as a key synthetic intermediate or potential pharmacophore for developing novel therapeutic agents, particularly in central nervous system (CNS) and oncology research. Pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers specializing in high-value intermediates are the primary users who need this high-purity building block.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of novel drug candidates targeting serotonin and tryptamine receptors.
• Neurological Research: Used in the development of potential neuroprotective agents, antidepressants, or anxiolytics due to its structural similarity to endogenous indoleamines.
• Oncological Research: Investigated as a scaffold for creating compounds with potential anti-proliferative or apoptosis-inducing activity against cancer cell lines.
• Chemical Biology Probe: Utilized as a tool compound to study protein-ligand interactions and signaling pathways involving indole-based recognition.
• Academic & Institutional Research: Employed in universities and research institutes for methodological studies in heterocyclic and medicinal chemistry.
• Process Chemistry Development: Acts as a model compound for scaling up and optimizing complex multi-step synthetic routes in fine chemical production.

Basic Information

Product Name	n-[2-(5-Fluoro-1H-Indol-3-Yl)Ethyl]-2-(1H-Indol-3-Yl)Acetamide
CAS No.	920430-43-9
Molecular Formula	C20H18FN3O
Molecular Weight	335.38 g/mol
Synonyms	5-Fluoro-N-[2-(1H-indol-3-yl)ethyl]-1H-indole-3-ethanamine; 2-(1H-Indol-3-yl)-N-[2-(5-fluoro-1H-indol-3-yl)ethyl]acetamide; 1H-Indole-3-ethanamine, 5-fluoro-N-[2-(1H-indol-3-yl)ethyl]-; Bis-indole acetamide derivative; 5-Fluoro-tryptamine-tryptamide; F-IAA-Tryp amide; N-(2-(5-Fluoro-1H-indol-3-yl)ethyl)-2-(1H-indol-3-yl)acetamide
EINECS	Contact for details

Quality Control

Our n-[2-(5-Fluoro-1H-Indol-3-Yl)Ethyl]-2-(1H-Indol-3-Yl)Acetamide is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant ICH guidelines for stability and impurity characterization to support regulatory filings.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to prevent decomposition. Keep the container sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.