Description

5-Thiazolepropanoic Acid, 2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]- is a high-purity, advanced pharmaceutical intermediate with a protected amino acid moiety. This compound is critical for the synthesis of complex molecules, offering a versatile building block for medicinal chemistry research and development. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the production of novel active pharmaceutical ingredients (APIs) and therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs.
• Peptide Mimetics Synthesis: Used to incorporate thiazole-based heterocycles into peptide backbones, creating mimetics with enhanced stability or biological activity.
• Protease Inhibitor Development: Serves as a crucial component in the design and synthesis of protease inhibitor libraries for therapeutic screening.
• Chemical Biology Probes: Employed in the construction of specialized probes for studying enzyme mechanisms and protein interactions.
• Agrochemical Research: Acts as a building block for developing novel compounds with potential herbicidal or pesticidal activity.
• Material Science: Investigated for the synthesis of specialized polymers or ligands with unique coordination properties.

Basic Information

Product Name	5-Thiazolepropanoic Acid, 2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]-
CAS No.	920313-46-8
Molecular Formula	C11H16N2O4S
Molecular Weight	272.32 g/mol
Synonyms	2-[(tert-Butoxycarbonyl)amino]-5-thiazolepropanoic acid; Boc-5-Thiazolepropanoic acid; 2-(Boc-amino)-1,3-thiazole-5-propanoic acid; 2-[[(1,1-Dimethylethoxy)carbonyl]amino]-1,3-thiazole-5-propanoic acid; tert-Butyl N-(5-(2-carboxyethyl)-1,3-thiazol-2-yl)carbamate; 920313-46-8; Boc-Azt-OH (common abbreviation); 2-Amino-5-thiazolepropionic acid Boc-protected derivative
EINECS	Contact for details

Quality Control

Our 5-Thiazolepropanoic Acid, 2-[[(1,1-Dimethylethoxy)Carbonyl]Amino]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with each shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.