Description

1H-Indole-3-Carboxylic Acid, 6-Chloro-5-Fluoro- is a high-purity, halogenated indole derivative serving as a critical building block in advanced organic synthesis. This compound matters for its role as a key intermediate in the development of novel pharmaceuticals and agrochemicals, where its unique molecular scaffold enables the creation of compounds with targeted biological activity. It is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for the synthesis of active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly in oncology and central nervous system (CNS) therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its halogenated structure for enhanced bioactivity.
• Organic Light-Emitting Diode (OLED) Materials: Serves as a building block for electron-transport or host materials in the manufacture of high-performance display technologies.
• Biochemical Research: Employed as a standard or reagent in biochemical assays and proteomics research to study enzyme inhibition and signal transduction pathways.
• Ligand Synthesis for Catalysis: Utilized in the preparation of specialized ligands for transition metal catalysis, enabling more efficient and selective chemical transformations.
• Fluorescent Probe Development: Acts as a core structure for developing sensitive fluorescent probes and markers used in cellular imaging and diagnostic applications.

Basic Information

Product Name	1H-Indole-3-Carboxylic Acid, 6-Chloro-5-Fluoro-
CAS No.	920023-30-9
Molecular Formula	C9H5ClFNO2
Molecular Weight	213.59 g/mol
Synonyms	6-Chloro-5-fluoro-1H-indole-3-carboxylic acid; 5-Fluoro-6-chloroindole-3-carboxylic acid; 6-Chloro-5-fluoroindole-3-carboxylic acid; 1H-Indole-3-carboxylic acid, 6-chloro-5-fluoro-; 920023-30-9; 6-Cl-5-F-1H-indole-3-COOH
EINECS	Contact for details

Quality Control

Our 1H-Indole-3-Carboxylic Acid, 6-Chloro-5-Fluoro- is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specified parameters to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. Due to its light-sensitive nature, handling should be performed under appropriate conditions to minimize exposure.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.